Diclofenac/Misoprostol is a combination medication used primarily to treat symptoms of osteoarthritis and rheumatoid arthritis in patients at high risk of developing NSAID-induced gastric ulcers. It combines:

Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), which reduces pain and inflammation.

Misoprostol, a prostaglandin analog, which helps protect the stomach lining by reducing acid secretion and increasing mucus production.

This combination allows patients to receive effective anti-inflammatory treatment while minimizing gastrointestinal side effects commonly associated with long-term NSAID use.